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Rank #22 ITN Score: 17/30

Antimicrobial Resistance

Antimicrobial resistance erodes the effectiveness of the antibiotics that underpin modern medicine, causing millions of deaths annually. A broken antibiotic-development market and the evolutionary inevitability of resistance make it a slow-burn, hard-to-solve global threat.

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Antimicrobial resistance (AMR) threatens to unwind a century of medical progress, rendering routine infections, surgery, and chemotherapy dangerous once again. This founding report quantifies the global burden, diagnoses the broken antibiotic-development market at the heart of the problem, and lays out a research and policy agenda spanning stewardship, surveillance, novel incentive models, and the One Health interface.

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